Safety and efficacy of vaginal hysterectomy in the large uterus with the LigaSure bipolar diathermy system. Posted on 1 November 200814 February 2020 by admin Mistrangelo E, Febo G, Ferrero B, Ferrero S, Deltetto F, Camanni M. Safety and efficacy of vaginal hysterectomy in the large uterus with the LigaSure bipolar diathermy system. Am J Obstet Gynecol 2008;199:475.e1-e5.https://www.ajog.org/article/S0002-9378(08)00289-5/fulltext